With my project, I started with a series of wooden sawhorses and made a long rectangular frame like a ladder, this was levelled and then nailed off to the floor with x bracing to help counter any twisting at a later date. With the centreline longerons cut into the bulkheads and using a long line on the floor it isnt very hard to drop a plumb bob at each frame (so long as you dont sand away the marked top and bottom centrelines when making each bulkhead...not that it ever happened to me mind you

) Once you are happy with the positioning, use a nail gun to drive blocks either side of the longeron where it crosses the ladder x members. After that it isnt going very far.
You can get the longerons level if required with small packers tucked under.
Hint, dont lean sheets of ply against the front of the frame. It explains why the whole frame gets suddenly out of kilter. (Not that it ever happened to me tho'

)
The main reason I went this way is that I can then still lift the fuselage up (and with some helpers) remove the x members (screw these in , not nail) and rejig the fuselage upside down to skin the lower side, the cross members then support the longerons in the same way.. After that, Ill be installing the U/c legs before I install much of the interior fittings and then sheet the sides.
If I had more space and was doing more than 1 fuselage id certainly consider making up jigs like Kolomans as theyre the ducks nuts for stability.
On the plus side, after 2 months delay I just took delivery of my next load of 1.5mm and 3mm ply to skin the rest of the fusleage

. I just need to get through the next 2 weekends of medieval shows and I can get stuck in again.
chris